Differin Cream 30 gm A topical cream containing 0.1% adapalene, a third-generation retinoid used to treat acne. It works by regulating skin cell turnover, helping to prevent clogged pores and reduce the formation of pimples and blackheads. Apply a thin layer to affected areas in the evening after cleansing and drying the skin. Initial use may cause mild dryness or peeling; using a suitable moisturizer is recommended